Glycoproteins and Disease
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Glycoproteins and Disease

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ISBN-13:
9780444823960
Einband:
Buch
Erscheinungsdatum:
01.10.1996
Seiten:
486
Autor:
J. Montreuil
Serie:
30, International Congress Series
Sprache:
Englisch
Beschreibung:

The elucidation during the latter half of the 20th century of the mechanisms by which information flows from nucleic acids to proteins has completely changed the face of biological research. This volume discusses several representative diseases which emphasize the status of glycopathology.
Preface. List of contributors. Previous volumes in the series. Preliminary contents of volume 29b. Introduction to the volume (A. Kobata). 1a. Normal and Pathological catabolism of glycoproteins. The enzymes (G.W. Jourdian). 1b. Normal and pathological catabolism of glycoproteins. Catabolic pathways (J.-C. Michalski). 2a. Glycoproteins of parasites. Glycoproteins of Trypanosoma cruzi (B.K. Hayes, G.W. Hart). 2b. Glycoproteins of parasites. Glycoconjugates of Leishmania (S.J. Turco). 2c. Glycoproteins of parasites. Glycoproteins of malaria parasites (A. Dieckmann-Schuppert, P. Gerold, R.T. Schwarz). 2d. Glycoproteins of parasites. Schistosoma glycoconjugates and their role in host-parasite pathological interactions (G.J. van Dam, A.M. Deelder). 3. Cancer cells and metastasis. Introduction (A. Kobata). 3a. Cancer cells and metastasis. Choriocarcinoma and hCG (R. Nishimura, A. Kobata). 3b. Cancer cells and metastasis. Hepatocellular carcinoma (K. Yamashita, A. Kobata). 3c. Cancer cells and metastasis. The Warren-Glick phenomenon - a molecular basis of tumorigenesis and metastasis (A. Kobata). 3d. Cancer cells and metastasis. Carcinoembryonic antigen and related normal antigens. (K. Yamashita, A. Kobata). 3. Cancer cells and metastasis. Concluding remarks (A. Kobata). 4. Tumor-associated carbohydrate antigens and modified blood group antigens (S. Hakomori). 5. Rheumatoid arthritis and serum IgG (T. Endo, K. Furukawa). 6. Glycoproteins in inflammatory bowel disease (M. Tomana). 7. HEMPAS: A genetic disorder caused by a defect in N- linked oligosaccharide synthesis (M.N. Fukuda). 8. Leukosialin and the Wiskott-Aldrich syndrome (M. Fukuda). 9. Progeroid form of Ehlers-Danlos syndrome (H. Kresse). 10. Paroxysmal nocturnal hemoglobinuria (M. Tomita). 11. Human mucosal mucins in diseases (P. Roussel, G. Lamblin). 12. Glycoproteins and lectins in multiple sclerosis and immune demyelinating human diseases (J.-P. Zanetta). 13. Leucocyte adhesion deficiency Type II (J.C. Paulson). 14. Polysialic acids of vertebrates: biosynthesis, structural diversity, tissue expression and functions (J. Roth). 15. Glycosylation defects in blood clotting (M. Matsuda). 16a. Carbohydrate-deficient glycoprotein syndrome. Type I (K. Yamashita, K. Ohno). 16b. Carbohydrate-deficient glycoprotein syndrome. Type II: an autosomal recessive disease due to mutations in the N-acetylglucosaminyltransferase II gene (J. Jaeken, G. Spik, H. Schachter). Index.
The elucidation during the latter half of the 20th century of the mechanisms by which information flows from nucleic acids to proteins has completely changed the face of biological research. This volume discusses several representative diseases which emphasize the status of glycopathology.