Human Genetic Diversity: Functional Consequences for Health and Disease
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Human Genetic Diversity: Functional Consequences for Health and Disease

 Taschenbuch
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ISBN-13:
9780199227709
Einband:
Taschenbuch
Erscheinungsdatum:
01.10.2009
Seiten:
432
Autor:
Julian C. Knight
Gewicht:
1098 g
Format:
244x188x23 mm
Sprache:
Englisch
Beschreibung:

1. Lessons From Haemoglobin ; 2. Finding Genes and Specific Genetic Variants Responsible for Disease ; 3. Cytogenetics and Large Scale Structural Genomic Variation ; 4. Submicroscopic Structural Variation in Health and Susceptibility to Disease ; 5. Submicroscopic Structural Variation and Genomic Disorders ; 6. Segmental Duplications and Indel Polymorphisms ; 7. Tandem Repeats ; 8. Mobile DNA Elements ; 9. SNPs, HapMap and Common Disease ; 10. Fine Scale Sequence Diversity and Signatures of Selection ; 11. Genetics of Gene Expression ; 12. Extreme Diversity in the Major Histocompatibility Complex ; 13. Parasite Wars ; 14. Human Genetic Diversity and HIV: Lessons From a War Fought on Many Fronts ; 15. Concluding Remarks and Future Directions ; Glossary ; References ; Index
This book describes the remarkable progress which has been made in defining the extent and nature of human genetic variation. It provides a framework for understanding how research in this area is revolutionising our knowledge of human origins and the genetic basis of disease, as well as common traits such as obesity.